Fosmicin: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Fosfomycin Na

Indications/Uses

Infections due to fosfomycin-susceptible strains of Pseudomonas aeruginosa, Proteus sp, Serratia marcescens, & multidrug resistant strains of Staph aureus & E. coli in septicemia, infection of resp, urogenital & abdominal tracts, bones, lymph node, head injuries & meningitis.

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Dosage/Direction for Use

IV Administer as IV drip infusion over 1-2 hr period. Adult 2-4 g in 2 divided doses daily. Childn 100-200 mg/kg in 2 divided doses daily. Renal dysfunction w/ CrCl 80-100 mL/min 2 g/12 hr, 40-50 mL/min 1 g/12 hr, 20-30 mL/min 500 mg/12 hr.

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Contraindications

History of hypersensitivity.

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Special Precautions

Discontinue treatment when symptoms of shock eg, chest anxiety, dyspnea, decreased BP, cyanosis, urticaria & discomfort occur; jaundice appears. Phlebitis & angialgia following IV administration. Patients whose parents or siblings are predisposed to develop allergic reactions eg, bronchial asthma, rash & urticaria. Periodically perform liver & kidney function tests as well as hematological tests in patients on long term therapy. Patients on restricted Na diet. Liver disorders. Avoid use during pregnancy.

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Use In Pregnancy & Lactation

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Adverse Reactions

Shock; jaundice.

Drug Interactions

Lowered serum conc & urinary excretion w/ metoclopramide; other drugs that increase GI motility.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Fosmicin detailed prescribing information

Storage

View Fosmicin storage conditions for details to ensure optimal shelf-life.

Description

View Fosmicin description for details of the chemical structure and excipients (inactive components).

Action

View Fosmicin mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Antibiotics

ATC Classification

J01XX01 - fosfomycin ; Belongs to the class of other antibacterials. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Fosmicin powd for inj 2 g

Packing/Price

10 × 1's

Form

Fosmicin Powd for inj 4 g

Packing/Price

10 × 1's

Fosmicin

fosfomycin

Manufacturer:

Meiji

Distributor:

Zuellig Pharma