Femorum Inj Dosage/Direction for Use

Adults and the Elderly: The total cumulative dose of medicine, equivalent to the total iron deficit (mg), is determined by the haemoglobin level and body weight. The dose for medicine must be individually determined for each patient according to the total iron deficit calculated with the following formula: See Equation 1.

Click on icon to see table/diagram/image

The total amount of Femorum lnjection required in mg is determined from Equation 1.
Alternatively, the total amount of Femorum lnjection required in mL is determined from Equation 2 or Table.

Click on icon to see table/diagram/image


Click on icon to see table/diagram/image

To convert Hb (mM) to Hb (g/L), multiply the former by 16.1145.
Dosage: The total single dose must not exceed 200 mg of iron given not more than three times per week. If the total necessary dose exceeds the maximum allowed single dose, then the administration has to be split.
Children: The use of Femorum lnjection has not been adequately studied in children and, therefore, Femorum lnjection is not recommended for use in children.
Intravenous Drip Infusion: Femorum lnjection must be diluted only in sterile 0.9% w/v sodium chloride solution: in max. 100 mL sterile 0.9% w/v sodium chloride solution per 1 ampoule of Femorum lnjection (100 mg as Fe).
Dilution must take place immediately prior to infusion and the solution should be administered as follows: 100 mg iron (5 mL Femorum lnjection) in at least 15 minutes, 200 mg iron (10 mL Femorum lnjection) in at least 30 minutes.
The first 25 mg of iron (i.e. 25 mL of solution) should be infused as a test dose over a period of 15 minutes. If no adverse reactions occur during this time then the remaining portion of the infusion should be given at an infusion rate of not more than 50 mL in 15 minutes.
Intravenous Injection: Femorum lnjection may be administered by slow intravenous injection at a rate of 1 mL undiluted Femorum solution per minute and not exceeding 10 mL Femorum lnjection (200 mg iron) per injection.
Before administering a slow intravenous injection, a test dose of 1 mL (20 mg of iron) should be injected slowly over a period of 1 to 2 minutes. If no adverse events occur within 15 minutes of completing the test dose, then the remaining portion of the injection may be given.
lnjection into dialyser: Femorum lnjection may be administered during a haemodialysis session directly into the venous limb of the dialyser under the same procedures as those outlined for intravenous injection.
Administration: The drug must only be administered by the intravenous route. This may be by a slow intravenous injection or by an intravenous drip infusion. Before administering the first dose to a new patient, a test dose should be given, if allergic reaction or drug intolerance occurs, stop the treatment with this drug.
Femorum lnj. must not be used for intramuscular injection.