Health-care providers should confirm with patients, parents, or guardians about reactions to a previous dose of this product or similar product.
Appropriate medical treatments, such as adrenaline, should be readily available for immediate use in case of occasional severe anaphylactic reaction following vaccination. The recipients shall be observed for at least 30 minutes on site after injection.
Special care should be taken to guarantee the injection does not enter a blood vessel.
The vaccine should be administered with caution to people with blood disorders such as a decrease in platelets (thrombocytopenia) or clotting disorders since bleeding may occur following intramuscular administration of the vaccine.
People are taking a treatment that suppresses immune defenses (corticosteroid drugs, cytotoxic drugs, radiotherapy, or any other treatments likely to weaken immune defenses) or if patients present with immune deficiency (immunosuppression), the immune response to the vaccine may be reduced. In such cases, it is recommended to postpone vaccination until the end of the treatment or to make sure the subject is well protected.
The vaccine does not contain preservatives. Therefore, it should be administered immediately after the container is opened.
Do not use the vaccine if the vial has cracks, unclear or invalid label, abnormal color or foreign matter, or the color of the vaccine vial monitor (VVM) in the central square is the same color as the ring or darker.
As with any vaccine, a protective immune response may not be elicited in all recipients.
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