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Cycloserine Meiji

Cycloserine Meiji Mechanism of Action

cycloserine

Manufacturer:

Meiji

Distributor:

Zuellig Pharma
Full Prescribing Info
Action
PHARMACOLOGY: In vitro antibacterial activity: The minimum inhibitory concentrations (MICs) of cycloserine against human-type tubercle bacilli H37RV range from 6.25 to 12.5 μg/mL. (See Table 3.)

Click on icon to see table/diagram/image

PHARMACOKINETICS: Blood concentration: The mean blood concentration two hours after oral administration of 250 mg (potency) of the product to human (n=15) was 16.9 μg/mL (range: 6.0 to 26 μg/mL).
Excretion: After an oral single administration of 500 mg* of the product to human (n=9), a mean of 41% (19 to 92%) of the given dose was excreted within the first 24 hours. (Foreign data).
* The approved single dose of this product is 250 mg.
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