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Should avoid concomitant use of Lidocaine with Conivaptan and Saquinavir.
Increased effect/Toxicity: Lidocaine may increase the levels/effect of Prilocaine.
The levels/effect of Lidocaine may be increased by Abiraterone acetate, Amiodarone, Beta-blockers, Conivaptan, CYP1A2 inhibitors (Moderate), CYP1A2 inhibitors (Strong), CYP3A4 inhibitors (Moderate), CYP3A inhibitors (Strong), Darunavir, Dasatinib, Deferasirox, Disopyramide, Hyaluronidase, Ivacaftor, Mifepristone, Saquinavir, Telaprevir.
Decreased effect: The levels/effect of Lidocaine may be decreased by CYP1A2 inducers (Strong), CYP3A4 inducers (Strong), Cyproterone, Deferasirox, Etravirine, Herb (CYP3A4 inducers), Tocilizumab.
Interactions with Ethanol/Nutrition/Herb: Herb and Nutraceutical may decrease lidocaine levels/effect should avoid concurrent use.
