Camoxtin/Camoxtin ES Drug Interactions

Concomitant use with probenecid is not recommended. Probenecid decreases the renal tubular secretion of amoxicillin, concomitant using may result in increased and prolonged blood levels of amoxicillin but not clavulanic acid.
Concomitant use of allopurinol during treatment with amoxicillin can increase the likelihood of allergic skin reactions.
This medicine may affect the gut flora, leading to lower oestrogen reabsorption and reduced efficacy of combined oral contraceptives.
There are rare cases of increased international normalised ratio in patients maintained on acenocoumarol or warfarin and prescribed a course of amoxicillin. If co-administration is necessary, the prothrombin time or international normalised ratio should be carefully monitored with addition or withdrawal of this medicine.
In patients receiving mycophenolate mofetil, reduction in pre-dose concentration of the active metabolite mycophenolic acid of approximately 50% has been reported following commencement of oral administration of this medicine. The change in pre-dose level may not accurately represent changes in overall mycophenolic acid exposure.