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1. Do not use the drug during pregnancy.
2. Consult the physician if the symptoms of nausea and vomiting occurred.
3. If the face, tongue and lips edema or dyspnea occurred, discontinue the drug and consult physician.
4. The drug can caused renal failure; therefore it should be used with caution.
5. The drug may increase potassium level, therefore, it should not be used in patients who received potassium supplement or who recently used potassium sparing diuretics.
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