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Posology: Adults: daily dosage is 1 coated tablet cyanocobalamin 1000 µg for the treatment of clinical vitamin B12 deficiency. In severe cases an initial treatment with 2 coated tablets cyanocobalamin 1000 µg is recommended. In case of severe neurological symptoms, initial parenteral application is recommended.
Children and adolescents: In children and adolescents, oral cyanocobalamin in daily doses of up to 1000 µg are recommended as an alternative to parenteral therapy of vitamin B12 deficiency.
Elderly: Normal dosage regimens are recommended in the elderly.
Patients with hepatic impairment: Pharmacokinetic data and clinical experience on patients with hepatic impairment are not available. Safety and efficacy in patients with hepatic impairment have not been established.
Method of administration: The coated tablet should be swallowed whole with some fluid, preferably in the morning on an empty stomach. The treatment duration is determined by the therapeutic response.
A targeted diagnostics and therapy control should adjust the patient to an optimal dose of cyanocobalamin.
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