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Hypersensitivity to the active substance or to any of the excipients listed in Description.
Cyanocobalamin 1000 µg coated tablets must not be used in patients who are in need of cyanide detoxification (e.g. patients with tobacco amblyopia or retrobulbar neuritis in pernicious anaemia). In this situation, other cobalamin derivatives should be administered.
B12-deficient individuals who are at risk for Leber's optic atrophy should not be given cyanocobalamin to treat the B12 deficiency.
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