Antazallerge

Each mL contains Antazoline Hydrochloride 0.5 mg, Tetrahydrozoline Hydrochloride (INN: Tetryzoline HCl) 0.4 mg, Preservative: Benzalkonium Chloride 0.1 mg.

Pharmacology: Antazoline, the antiallergic active substances in ANTAZALLERGE (Eye Drops) is responsible for competitive blocking of the H₁ receptors and thus reduces the following effects of the histamine released in the tissue: increase in permeability and expansion of the capillaries and, to a certain extent contraction of smooth muscles.
Tetrahydrozoline acts as a vasoconstrictor and relieves irritation and swelling.
Because of these properties, ANTAZALLERGE (Eye Drops) is suitable for the treatment of allergic symptoms which are mainly induced by the release of histamine.
Tear secretion is slightly reduced while pupil diameter is slightly dilated.
Pharmacokinetics: Like all α-sympathomimetics, Tetrahydrozoline is absorbed systemically via the blood vessels. However, after topical administration of ANTAZALLERGE (Eye Drops) in the eye, the amounts absorbed are extremely small. H₁ antihistamines are generally absorbed rapidly and readily.

Irritant conjunctivitis, allergic conjunctivitis, particularly hay fever conjunctivitis and venal conjunctivitis.

In the acute stage, 1 drop every three hours; for continuous use, 1 drop 2-3 times daily. In severe cases, ANTAZALLERGE (Eye Drops) can be used as frequently as once an hour.

Contraindication to patient with hypersensitivity to the ingredients.
No studies have been carried out on the use of ANTAZALLERGE (Eye Drops) in pregnancy and lactation and for infants.
Patients wearing contact lenses may use the eye drops if medication is given while the lenses are not worn.
In patients with narrow-angle glaucoma application is in general not recommended.

A mild burning sensation may occur for a short time directly after instillation of the eye drops.
Headache, sleepiness and tachycardia may occur in isolated cases, especially in infants.
Hypersensitivity of the ingredients. In particular to antazoline may occur in very rare cases.

Store below 30°C.
Shelf-life: Close the bottle immediately after use. Do not use longer than one month after opening the bottle. If the pack is unopened.

Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories

S01GA52 - tetryzoline, combinations ; Belongs to the class of sympathomimetics used as ophthalmologic decongestants.

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