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Each vial contains: Amphotericin B 50 mg, sodium deoxycholate q.s. (as solubiliser), sodium phosphate (as buffer).
Amphotret (Amphotericin B for Injection U.S.P.) is a freeze dried preparation of Amphotericin B for intravenous injection. Amphotret (Amphotericin B for Injection U.S.P.) is a yellow coloured cake which is required to be reconstituted with Sterile Water for Injection before administration. Amphotericin B is a polyene macrolide antifungal antibiotic obtained from a strain of Streptomyces nodosus. Amphotericin B is insoluble in water at neutral pH and hence formulated as a colloidal dispersion using sodium deoxycholate as a solubiliser.
