Amphotret Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Amphotericin B

Indications/Uses

Progressive, potentially life-threatening fungal infections caused by Candida sp, Aspergillus sp, Cryptococcus neoformans, Mucor sp, Rhodotorula sp, Absidia sp, Blastomyces dermatitidis.

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Dosage/Direction for Use

0.5-1 mg/kg/day by slow IV infusion. Max: 1.5 mg/kg/day.

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Overdosage

View Amphotret overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity.

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Special Precautions

Regular monitoring of renal & liver function, serum electrolytes (especially Mg & K), blood counts & Hb conc. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nephrotoxicity, anemia, infusion related events & phlebitis.

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Drug Interactions

Concomitant use w/ anti-bacterials, immunosuppressants, parenteral pentamidine, antineoplastics & diuretics. May enhance effects of neuromuscular blocking agents & increase toxicity of digitalis glycosides. May enhance depletion of K & immunosuppresive effects w/ corticosteroids. Procaine HCl & lidocaine HCl, ranitidine HCl, antihistamines & vit.

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Storage

View Amphotret storage conditions for details to ensure optimal shelf-life.

Description

View Amphotret description for details of the chemical structure and excipients (inactive components).

Action

View Amphotret mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antifungals

ATC Classification

J02AA01 - amphotericin B ; Belongs to the class of antibiotics. Used in the systemic treatment of mycotic infections.

Thai FDA Category

Presentation/Packing

Form

Amphotret infusion 50 mg

Packing/Price

1's

Amphotret

amphotericin b

Manufacturer:

Bharat Serums and Vaccines

Distributor:

Cosma Medical