Ziprocap Special Precautions

Effects on ability to drive and use machines: Patients who drive and operate machines must not take ciprofloxacin with alcohol.
The risk of crystalluria is high in patients with alkaline urine.
Use in patients with renal impairment: Ciprofloxacin should be used with caution in patients with impaired renal function. Dose should be reduced when giving ciprofloxacin to patients with severe renal impairment. (See Dosage & Administration.)
Use in patients with hepatic impairment: Ciprofloxacin should be used with caution in patients with severe hepatic impairment where peak plasma concentration and serum half life may be increased.
Interference with laboratory results: In elderly patients treated with ciprofloxacin for urinary tract infections, a false positive reaction for urinary glucose (pseudoglycosuria) has been reported.
Use in Lactation: Ciprofloxacin is excreted in breast milk. It should be used in caution when given to breast feeding mothers as this was found to cause arthropathy in young animals. (See Contraindications)
Use in Elderly: Dose of ciprofloxacin should be reduced in the elderly as increased bioavailability and reduced renal clearance were seen probably due to absorption or first pass elimination.