Viatrex Dosage/Direction for Use

It is administered as the sodium salt by intermittent intravenous infusion over 30 minutes or by deep intramuscular injection. Doses are expressed in terms of the equivalent amount of ceftriaxone. It is usually given to adults in a dose of 1 to 2 g daily as a single dose or in two divided doses; in severe infections up to 4 g daily may be given. Children may be given 50 to 75 mg per kg body-weight daily in two divided doses; the total daily dose should not exceed 2 g. For the treatment of meningitis in children, ceftriaxone may be given in a dose of 100 mg per kg daily in two divided doses, sometimes with a loading dose of 75 mg per kg; the total daily dose should not exceed 4 g.
A single intramuscular dose of 250 mg is recommended for the treatment of gonorrhea in adult. For surgical infection prophylaxis in adults, a single dose of 1 g is administered 0.5 to 2 hours prior to surgery.
A reduction in dosage may be necessary in patients with severe renal failure and in those with both impaired renal and hepatic function; plasma concentrations should be monitored in such patients.