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Initial Dose: 1 vaginal tablet daily for 2 weeks. Maintenance Dose: 1 vaginal tablet twice a week.
Treatment may be started on any convenient day.
If a dose is forgotten, it should be taken as soon as the patient remembers. A double dose should be avoided.
For initiation and continuation of treatment of menopausal symptoms, the lowest effective dose for the shortest duration (see Precautions) should be used.
Vagifem may be used in women with or without an intact uterus.
During treatment especially during the first 2 weeks minimal absorption may be seen but as plasma estradiol levels after the first 2 weeks usually do not exceed postmenopausal levels the addition of a progestagen is not recommended.
Administration: Vagifem is administered intravaginally using the applicator.
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