Triderm Adverse Reactions

Adverse reactions to Betamethasone/Clotrimazole/Gentamicin (TRIDERM) Ointment therapy have been reported very rarely and include skin discoloration, hypochromia, burning, erythema, exudation and pruritus.
Of almost 1000 patients who received clotrimazole therapy topically for indicated dermatomycoses, 95% showed excellent local tolerance. Reported adverse reactions include, stinging, blistering, peeling, edema, urticaria and general irritation of the skin.
Treatment with gentamicin has produced transient irritation that usually did not require discontinuance of treatment.
The following local adverse reactions have been reported with the use of topical corticosteroids especially under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.
Systemic adverse reactions, such as vision blurred, have also been reported with the use of topical corticosteroids.