Ferrous sulfate, folic acid, vitamin B complex.
Trev Iron FAB is supplied as a yellow to dark orange powder inside EGC#1 Choco brown cap/caramel opaque body.
Each capsule contains: Ferrous Sulfate (Equivalent to 97.5 mg Elemental Iron), USP 325 mg; Folic Acid, USP 1 mg; Thiamine Mononitrate (Vitamin B1), USP 15 mg; Riboflavin (Vitamin B2), USP 10 mg; Pyridoxine (Vitamin B6), USP 10 mg; Cyanocobalamin (Vitamin B12), USP 10 mcg.
Hematinic.
Pharmacology: Trev Iron FAB capsule contains ferrous sulfate, folic acid, vitamins B1, B2, B6, B12. These nutrients are the essential catalysts in the synthesis, degradation and utilization of carbohydrates, amino acids and fats. These are also essential for healthy blood, synthesis of hemoglobin (an oxygen containing protein which gives blood its red color) and to prevent and treat Iron deficiency anemia. These are also required for the normal function of the nervous system and used as adjunct in the management of various neuromuscular disorders.
This medicine is used for the prevention and treatment of iron-deficiency anemia, folate deficiency, and for the lowering of plasma homocysteine. It is used to prevent and treat deficiencies of vitamin B1, B6, and B12 and as an adjunct in the management of neuromuscular pain.
This medicine is taken orally, one capsule daily with or without food.
If the patients have forgotten to take the medicine, just take the next dose and the subsequent doses at the usual recommended schedule. Do not double the dose unless recommended by the doctor.
If more than the recommended dosage has been given, consult the doctor or pharmacist immediately and observed any sign of possible overdosage.
Undesirable effects also occur.
Overdosage is signaled by dizziness, frequent urination, change in the color of the urine, black stools, constipation, diarrhea, abdominal pain, nausea, vomiting, redness of the skin, and itching.
Acute Iron overdosage (≥1,500 mg elemental iron for a 50 kg adult/day).
Vitamin B6 (dose range: 200-300 mg/day).
Other cases reported reversible sensory neuropathy and reversible peripheral neuropathy as a result of prolonged use.
This medication is contraindicated in patients who are allergic to any ingredient in the product.
Iron should be used cautiously in patients with a history of gastritis, peptic ulcer, and GI bleeding.
Administration of cyanocobalamin (Vitamin B12) in doses greater than 10 mcg daily may produce a hematological response in patients with folate deficiency.
Although B-complex vitamins are relatively non-toxic, adverse neurologic effects have been reported following chronic administration of high doses; long term and megadose (see possible symptoms of overdose in Overdosage).
Ferrous and other salts should not be given to patients receiving repeated blood transfusion or patients with anemias not produced by iron deficiency unless iron deficiency is also present.
Do not take this medicine if the patient is allergic (hypersensitive) to Vitamin B complex.
Do not take more than the recommended dose.
The patient should consult the doctor if any undesirable effects occur.
Undesirable effects are rare, but they may occur.
Tell the doctor immediately if the patient experiences any undesirable effect: dizziness, frequent urination, change in the color of the urine, black stools, constipation, diarrhea, abdominal pain, nausea, vomiting, redness of the skin, or itching.
Iron: Cefdinir; bisphosphonates; carbidopa/levodopa; entacapone; fluoroquinolone; levodopa; levothyroxine; methyldopa; mycophenolate mofetil; penicillamine; and tetracyclines: Iron may reduce absorption of these drugs.
Vitamin B1: Neuromuscular blocking agent (Tubocurarine chloride, Metocurine iodide, Pancuronium bromide and Vecuronium bromide) may be enhanced by high doses of Vitamin B1 although the clinical significance of this is unknown.
Vitamin B complex: Do not take phenobarbital or phenytoin together with Vitamin B Complex as it may reduce blood level. Concomitant intake of anticoagulant (e.g. warfarin, aspirin, etc) may result in enhanced anticoagulant (blood thinning) response.
Folic Acid: Methotrexate, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), such as ibuprofen, naproxen, or diclofenac can deplete Folic acid consumption.
Tell the doctor about any other medicines the patient is taking, including supplements and herbal products.
Place it in its original container and box before disposing in the garbage. These measures will help to protect the environment.
Store at temperatures not exceeding 30°C.
B03AE02 - iron, multivitamins and folic acid ; Belongs to the class of iron in other combinations. Used in the treatment of anemia.
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