The range of adverse effects associated with fluoroquinolone antibacterial agents is broadly similar to quinolones such as nalidixic acid. They most often involved the gastrointestinal tract, central nervous system or skin. Gastrointestinal disturbance include nausea, vomiting, diarrhea, abdominal pain and dyspepsia and are the most frequent adverse effects. Pseudomembranous colitis has been reported rarely. Headache, dizziness and restlessness are most common effect on the CNS.
Others include tremor, drowsiness, insomnia, nightmares and visual disturbance and more rarely, hallucinations, psychotic reactions, depression and convulsion. Peripheral neuropathy has occurred occasionally.