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Should overdosage of Tamsulosin HCl (Tamsumax) capsules lead to hypotension, support of the cardiovascular system is of first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position. If this measure is inadequate, then administration of intravenous fluids should be considered. If necessary, vasopressors should then be used and renal function should be monitored and supported as needed. Laboratory data indicate that tamsulosin hydrochloride is 94% to 99% protein bound; therefore, dialysis is unlikely to be of benefit.
One patient reported an overdose of thirty 0.4 mg Tamsulosin HCl (Tamsumax) capsules. Following the ingestion of the capsules, the patient reported a severe headache.
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