Sullivan Adverse Reactions

Tab 625 mg/Powd for oral susp 125 mg/31.25 mg/Powd for oral susp 250 mg/62.5 mg/Powd for oral susp 400 mg/57 mg: Hepatitis and cholestatic jaundice have been reported with the combination amoxicillin with clavulanic acid, the clavulanic acid component has been implicated erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, exfoliative dermatitis, nausea, vomiting, diarrhea, rashes and antibiotic associated colitis have been occasionally noted.
Tab 1 g: Significant: Diarrhea, fungal or bacterial superinfection, convulsions (at high doses or in patients with renal impairment), morbilliform rash (in) patients with mononucleosis). Rarely, crystalluria (IV), prothrombin time prolongation.
Blood and lymphatic system disorders: Hemolytic anemia, reversible agranulocytosis. Rarely, thrombocytopenia, reversible leucopenia or neutropenia.
Gastrointestinal disorders: Nausea, vomiting, indigestion, black hairy tongue.
Immune system disorders: Serum sickness-like syndrome, urticaria, hypersensitivity, vasculitis.
Infections and Infestations: Mucocutaneous candidiasis.
Investigations: Increased AST/ALT.
Nervous system disorders: Headache, dizziness, reversible hyperactivity.
Renal and urinary disorders: Interstitial nephritis.
Reproductive system and breast disorders: Vaginal mycosis.
Skin and subcutaneous tissue disorders: Rash, pruritus, Stevens-Johnson syndrome. Rarely, erythema multiforme.
Potentially Fatal: Severe hypersensitivity reactions, including anaphylactoid and severe cutaneous reactions (e.g., acute generalized exanthematous pustulosis); Clostridium difficile-associated diarrhea or pseudomembranous colitis. Rarely, hepatic dysfunction (e.g., cholestatic jaundice, hepatitis).