Pharmacology: Mechanism of Action: Blood volume expander: Albumin is an important regulator of the volume of circulating blood. It accounts for 70 to 80% of the colloid oncotic pressure of plasma. An infusion of albumin 5% is oncotically equivalent to an equal volume of human plasma and increases blood volume by an amount approximately equal to the volume of albumin infused; albumin 25% is oncotically equivalent to approximately 5 times the volume of human plasma and draws into the circulation an amount of fluid approximately 3.5 times the volume of albumin infused. Albumin provides a temporary increase in blood volume, which reduces hemoconcentration and blood viscosity.
Antihyperbilirubinemic: Albumin is a transport protein that reversibly binds both endogenous and exogenous substances including bilirubin, fatty acids, hormones, enzymes, drugs, dyes and trace metals.
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