Samitol Dosage/Direction for Use

Dosage: Urogenital trichomoniasis: 4 tablets of 500 mg in a day as a single dose or in two doses at an interval of 12 hours (total 2 g).
Amebiasis and acute intestinal giardiasis: 4 tablets of 500 mg in a day as a single dose or in two doses at an interval of 12 hours (total 2 g).
Chronic carriers of amoeba: 3 tablets of 500 mg per day in a several doses for 3 days.
Liver Amebiasis: 3 tablets of 500 mg per day in one or several doses for at least 5 days.
Children: According to medical criteria, 25-30 mg/kg/day. The duration of treatment is to same clinical situation, identical to adults.
In patients with renal or hepatic impairment, the recommended doses are the derivatives of 5-nitro-imidazole in general.
Thus, in case of moderate to severe renal impairment, the pharmacokinetics of Samitol is not significantly changed, so they are not usually necessary adjustments in dosage, particularly for short-term treatments.
If a patient with severe hepatic impairment, the physician must evaluate the situation and reduce the daily dose according to the severity of this.
In both cases, the physician's discretion, as usual, is decisive in these situations.
Mode of administration: Oral.