Saltrol Overdosage

Salmeterol: The signs and symptoms of Salmeterol overdose are dizziness, increases in systolic blood pressure, tremor, headache and tachycardia. If Salmeterol + Fluticasone propionate therapy has to be withdrawn due to overdose of the β agonist component of the drug, provision of appropriate replacement steroid therapy should be considered. Additionally, hypokalemia can occur and therefore serum potassium levels should be monitored. Potassium replacement should be considered.
Fluticasone propionate: Acute: Acute inhalation of Fluticasone propionate doses in excess of those recommended may lead to temporary suppression of adrenal function. This does not need emergency action as adrenal function is recovered in a few days, as verified by plasma cortisol measurements.
Chronic overdose of inhaled Fluticasone propionate: Adrenal reserve should be monitored and treatment with a systemic corticosteroid may be necessary. When stabilized, treatment should be continued with an inhaled corticosteroid at the recommended dose.
In cases of both acute and chronic Fluticasone propionate overdose, therapy should be continued at a suitable dosage for symptom control.