The usual initial dose of Rosuvastatin is 5 mg to 10 mg once daily, depending on plasma-cholesterol concentrations, cardiovascular risk factors, and risk factors for adverse effects. The maintenance dose ranges from 5 to 40 mg once daily, although the 40 mg dose is reserved for patients with high cardiovascular risk factors who do not achieve their target cholesterol concentration at lower classes and who do not have risk factors for adverse effects. Or as prescribed by the physician.