Rophin Dosage/Direction for Use

Ceftriaxone is given as the sodium salt by slow intravenous injection over at least 2 to 4 minutes, by intermittent intravenous infusion over at least 30 minutes, or by deep intramuscular injection. If more than 1 g is to be injected intramuscularly then the dose should be divided between more than one site.
The usual adult dose is 1 to 2 g daily as a single dose or in two divided doses; in severe infections, up to 4 g daily may be given.
Doses for infants and children (under 50 kg) are 20 to 50 mg/kg once daily; for severe infections up to 80 mg/kg daily may be given.
In neonates, the maximum dose should not exceed 50 mg/kg daily; intravenous doses in neonates should be given over 60 minutes.
Doses above 50 mg/kg should be given by intravenous infusion only.
For the treatment of uncomplicated gonorrhoea, a single intramuscular dose of 250 mg is recommended.
For surgical infection prophylaxis, a single dose of 1 g may be given 0.5 to 2 hours before surgery; a 2-g dose is suggested before colorectal surgery.
For the prevention of secondary cases of meningococcal meningitis, a single intramuscular dose of 250 mg may be used for adults and 125 mg for children.