Ceftriaxone is used for the treatment of susceptible infections such as chancroid, endocarditis, gastroenteritis (invasive salmonellosis; shigellosis), gonorrhoea, Lyme disease, meningitis (including meningococcal meningitis prophylaxis), pneumonia, septicaemia, syphilis, typhoid fever, and Whipple's disease. It is also used for surgical infection prophylaxis.