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Clear, colourless to slightly yellowish liquid with pH of 6.3-6.7 and osmolality of ≥240 mOsm/kg.
Rituximab is a genetically engineered chimeric mouse/human monoclonal antibody representing a glycosylated immunoglobulin with human IgG1 constant regions and murine light-chain and heavy-chain variable region sequences. The antibody is produced by mammalian (Chinese hamster ovary) cell suspension culture and purified by affinity chromatography and ion exchange, including specific viral inactivation procedures.
100 mg: Each 10 mL Concentrate for Solution for Infusion (IV) contains: Rituximab 100 mg.
500 mg: Each 50 mL Concentrate for Solution for Infusion (IV) contains: Rituximab 500 mg.
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