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Gastrointestinal: Abdominal pain, constipation, diarrhea, flatulence, indigestion, vomiting, duodenal ulcer disease, esophageal erosions, esophageal perforation, esophageal stricture, esophagitis, gastric ulcer, ulcerative pharyngitis (acute), ulcer of esophagus.
Immunologic: Hypersensitivity reaction.
Musculoskeletal: Arthralgia, aseptic necrosis of bone of jaw, bone pain, myalgia, joint swelling, low-energy femoral shaft fracture.
Skin: Rash (occasionally with photosensitivity), pruritus, alopecia, rarely severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.
Special Senses: Rarely uveitis, scleritis or episcleritis.
Other: Fever, influenza-like symptoms, disturbances in serum electrolytes may occur, most commonly hypocalcemia and hypophosphataemia.
Other rare adverse effects include blood disorders such as anemia, thrombocytopenia, leucopenia and disturbances in liver enzyme values.
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