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Risperidone may be given in 1 or 2 divided doses daily. The usual initial daily dose of risperidone is 2 mg; this may be increased to 4 mg daily on the second day, and subsequently adjusted further as required in increments or decrements of 1 or 2 mg daily, generally at intervals of not less than one week.
Most patients benefit from doses of 4 to 6 mg daily.
Extrapyramidal symptoms may be more likely with doses above 10 mg daily; daily doses above 8 mg if divided into 2 doses is not recommended, although higher doses are permitted if given as a single dose. The maximum recommended dose is 16 mg daily.
An initial dose of 0.5 mg twice daily slowly increased in steps of 0.5 mg twice daily if necessary to a dose of 1 to 2 mg twice daily is recommended for the elderly and for patients with renal or hepatic impairment.
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