Ca-3-methyl-2-oxo-valerate (α-ketoanalogue to isoleucine, Ca salt) 67 mg, Ca-4-methyl-2-oxo-valerate (α-ketoanalogue to leucine, Ca salt) 101 mg, Ca-2-oxo-3-phenyl-propionate (α-ketoanalogue to phenylalanine, Ca salt) 68 mg, Ca-3-methyl-2-oxo-butyrate (α-ketoanalogue to valine, Ca salt) 86 mg, Ca-DL-2-hydroxy-4-(methylthio) butyrate (α-hydroxyanalogue to methionine, Ca salt) 59 mg, L-lysine acetate (equiv to 75 mg L-lysine) 105 mg, L-threonine 53 mg, L-tryptophan 23 mg, L-histidine 38 mg, L-tyrosine 30 mg. Total nitrogen content: 36 mg, Ca: 1.25 mmol equiv to 0.05 g
Prevention & therapy of damage due to faulty or deficient protein metabolism in chronic renal insufficiency in connection w/ limited protein in food of ≤40 g/day in patients w/ GFR <25 mL/min.
Adult >70 kg 4-8 tab tid as long as GFR is 5-50 mL/min & simultaneous food contains ≤40 g daily of protein.
Should be taken with food: Swallow whole.
Hypersensitivity to ≥1 amino acid or idiosyncratic reaction to ketoanalogues of essential amino acids. Metabolic disorders associated w/ impaired nitrogen utilization; hypercalcemia, disturbed amino acid metabolism. Severe liver diseases & hepatic coma.
Caution in patients w/ severe heart disease; known to be hypersensitive or who have had previous hypersensitivity. Ensure sufficient supply of cal. Regular evaluation of serum Ca level & lab determinations are necessary for proper monitoring of patients during treatment. Parenteral regimens should include non-protein cal adequate for wt maintenance if patient requires extended period of nutritional support. Exercise caution when prescribing to pregnant women. No experience w/ use during lactation.
Hypercalcemia; generalized flushing, fever & nausea. Fever, nausea, vomiting, abdominal pain, diarrhea & fatigue may occur at the beginning of therapy.
May lead to pathological increase of serum Ca level or intensification w/ simultaneous administration of Ca-containing medicaments. Absorption may be interfered w/ sparingly soluble compd w/ Ca (eg, tetracycline).
A16AA - Amino acids and derivatives ; Used in treatment of alimentary tract and metabolism problems.
Renoguard FC tab 600 mg
100's (P25.89/film-coated tab)
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