Rasator 0.5/Rasator 1 Dosage/Direction for Use

General Dosing Recommendation: Rasator 0.5: The recommended initial dose in patients taking levodopa, with or without other Parkinson's disease drugs (e.g., dopamine agonist, amantadine, anticholinergics) is 500 mcg once daily. If the patient tolerates the daily recommended dose, but a clinical response is not achieved, the dose may be increased to 1 mg daily. When used in combination with levodopa, a reduction of levodopa dose may be considered, based upon individual response. The recommended doses should not exceed because risk of hypertension may occur. May be taken with or without food.
Rasator 1: When prescribed as monotherapy or as an adjunct therapy in patients not taking Levodopa, patients may start at the recommended dose of 1 mg administered orally once daily.
The recommended initial dose in patients taking levodopa, with or without other Parkinson's disease drugs (e.g., dopamine agonist, amantadine, anticholinergics) is 500 mcg once daily. If the patient tolerates the daily recommended dose, but a clinical response is not achieved, the dose may be increased to 1 mg daily. When used in combination with levodopa, a reduction of levodopa dose may be considered, based upon individual response. The recommended doses should not exceed because risk of hypertension may occur. May be taken with or without food.
Patients with Hepatic Impairment: Patients with hepatic impairment should not exceed a dose 500 mcg once daily. Should not be used in patients with moderate to severe hepatic impairment.
Renal impairment: No special precautions are required in patients with renal impairment.
Elderly: No dose adjustment is required for elderly.