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Hypersensitivity to the active substance or to any of the excipients listed.
Severe renal impairment (creatinine clearance < 30 ml/min).
Moderate or severe hepatic impairment.
Concomitant administration of potent CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, voriconazole, posaconazol, HIV protease inhibitors, clarithromycin, telithromycin, nefazodone).
Concomitant administration of Class la (e.g. quinidine) or Class Ill (e.g. dofetilide, sotalol) antiarrhythmics other than amiodarone.
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