Qtipine 25/Qtipine 300 Adverse Reactions

The most frequent adverse effects with quetiapine are somnolence, dizziness, constipation, orthostatic hypotension, dry mouth, and raised liver enzyme values. Quetiapine has been associated with a low incidence of extrapyramidal symptoms. Rises in prolactin concentrations may be less than with chlorpromazine. Weight gain particularly during early treatment has also been noted. Clinical monitoring for hyperglycemia has been recommended, especially in patients with or at risk of developing diabetes. Neuroleptic malignant syndrome is rare with quetiapine but tardive dyskinesia may occur after long-term treatment. Tachycardia and occasionally, syncope have been reported; prolongation of the QT interval is rarely significant. Leucopenia, neutropenia, and eosinophilia have also been reported with quetiapine.
Other adverse effects have included mild asthenia, anxiety, fever, hypertension, myalgia, rhinitis, dyspepsia, rises in plasma- triglyceride and cholesterol concentrations, and reduced plasma thyroid hormone concentrations. There have been rare reports of seizures, hypersensitivity reactions including angioedema, priapism, and peripheral edema. Asymptomatic changes in the lens of the eye have occurred in patients during long-term treatment with quetiapine.