PTZ 2.25/PTZ 4.5 Caution For Usage

Direction for Reconstitution: Each vial of Piperacillin/Tazobactam 4 g/0.5 g Powder for Solution for Infusion should be reconstituted with 20 mL of one of the following diluents: Sterile water for injections; 0.9% sodium chloride for injection.
To achieve effective reconstitution, invert and shake the vial thoroughly to detach any powder adhering to the walls prior to addition of the diluent. Add the solvent and shake until complete dissolution is achieved.
The reconstituted solution should be further diluted to at least 50 mL with one of the reconstitution diluents, or with Dextrose 5% in Water.
Each vial of Piperacillin/Tazobactam 2 g/0.25 g Powder for Solution for Infusion should be reconstituted with 10 mL of one of the following diluents: Sterile water for injections; 0.9% sodium chloride for injection.
To achieve effective reconstitution, invert and shake the vial thoroughly to detach any powder adhering to the walls prior to addition of the diluent. Add the solvent and shake until complete dissolution is achieved.
The reconstituted solution should be further diluted to the concentration range of 13.33/1.67 mg/mL to 80/10 mg/mL with following diluents: Sterile Water for Injection; 9 mg/mL (0.9%) Sodium Chloride for Injection; Dextrose 50 mg/mL (5%) in water; Dextrose 5% in 0.9% Sodium chloride solution.
For single use only. Discard any unused solution.
The reconstitution/dilution is to be made under aseptic conditions. The reconstituted solution is to be inspected visually for particulate matter and discoloration prior to administration. The solution should only be used if the solution is clear and free from particles.