Swallow capsule whole. Do not open, chew or crush the capsule. Tamsulosin extended-release pellets are packed in hard capsules. Changes in pharmacokinetics may occur if the pellets are taken without the enclosing capsule.
Usual Oral Adult Dose in BPH: 400 mcg once daily, to be taken about 30 minutes after the same meal each day.
If the patient is unable to tolerate 400 mcg, then the patient should receive 200 mcg once daily.
Dose may be increased to 800 mcg once daily in patients who fail to respond to the 400 mcg dose after 2 to 4 weeks of dosing.
In case tamsulosin therapy (at either 400 mcg or 800 mcg) is discontinued or interrupted for several days, tamsulosin should be restarted with the 400 mcg once daily dose. Tamsulosin 400 mcg should not be used with strong inhibitors of CYP3A4 such as ketoconazole (see Precautions).
Missed Dose: If a dose is missed, take the next dose later the same day. If a day is missed, skip the missed dose and the regular dosing schedule be resumed. Do not double the dose to “make-up” for the dose that was missed.
400 mcg: Recommended Dose in Medical Expulsion Therapy: 400 mcg once daily.
The effect of tamsulosin may be observed starting 1 to 2 weeks of therapy. However, treatment for least 1 month may be necessary depending on patient's response and tolerance.
Tamsulosin should only be used in patients who are comfortable with this approach and when there is no obvious advantage from immediate active stone removal.
Or as prescribed by a physician.
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