Prozelax

Treatment of the functional signs & symptoms of benign prostatic hyperplasia (BPH) including bladder outlet obstruction.

SR cap Adult BPH 400 mcg once daily 30 min after same meal each day, or 200 mcg once daily in patients unable to tolerate. May be increased to 800 mcg once daily in patients who fail to respond to 400 mcg after 2-4 wk. Cap Adult BPH 400 mcg once daily 30 min after same meal each day, or 200 mcg once daily in patients unable to tolerate. May be increased to 800 mcg once daily in patients who fail to respond to 400 mcg after 2-4 wk. Medical expulsion therapy: 400 mcg once daily for 1-2 wk or at least 1 mth.

May be taken with or without food: Swallow cap whole, do not open/chew/crush. 400-mcg cap: Take approx 30 min after the same meal each day.

Hypersensitivity. Orthostatic hypotension. Severe hepatic insufficiency.

BP reduction. Orthostatic hypotension. Avoid situations where injury can result to syncope. Prostate cancer. Priapism & ejaculation disorders. Intraoperative floppy iris syndrome. Sulfa allergy. May affect ability to drive or operate machinery. Hepatic & renal impairment. Infant & childn. Elderly.

Headache, infection (including cold, common cold, flu & flu–like symptoms), asthenia, pain, back pain, chest pain, abdominal pain, accidental injury, flu syndrome, neck pain, fever, chills, malaise, fatigue. HTN, palpitations, hypotension, postural hypotension, tachycardia, atrial fibrillation, arrhythmia. Diarrhea, dyspepsia, vomiting, nausea, constipation, dry mouth, tooth disorder. Peripheral edema. Arthralgia, myalgia, arthritis. Dizziness, dizziness (aggravated), dizzy spell, vertigo, syncope, orthostatic/circulatory collapse, somnolence, insomnia, depressed level/loss of consciousness, hypertonia, paresthesia. Rhinitis, pharyngitis, increased cough, sinusitis, dyspnea, lung disorder, epistaxis. Allergic type reactions eg, skin rash, urticaria, pruritus, angioedema & resp symptoms, skin desquamation, sweating, erythema multiforme, dermatitis exfoliative & Stevens-Johnson syndrome. Abnormal ejaculation, decreased libido, priapism, reduced semen vol, UTI, dysuria, impotence. Blurred vision & visual impairment.

Ketoconazole, erythromycin, paroxetine, terbinafine. α-adrenergic blocking agents. May lower BP & cause hypotension w/ PDE5 inhibitors. Warfarin. Cimetidine.

Drugs for Bladder & Prostate Disorders

G04CA02 - tamsulosin ; Belongs to the class of alpha-adrenoreceptor antagonists. Used in the treatment of benign prostatic hypertrophy.

Rx