ProNorm Adverse Reactions

The following adverse events were observed and have been reported in patients using propranolol.
Cardiovascular: bradycardia, congestive heart failure, intensification of AV block, hypotension, paresthesia of hands, thrombocytopenic purpura, arterial insufficiency, usually of the Raynaud type.
Central Nervous System: light-headedness, mental depression, manifested by insomnia, lassitude, weakness, fatigue, catatonia; visual disturbances, hallucinations, vivid dreams, an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional liability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose-related.
Gastrointestinal: nausea, vomiting epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric, arterial thrombosis, ischemic colitis.
Allergic: hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis, erythematous rash, fever combined with aching and sore throat, laryngospasm, and respiratory distress.
Respiratory: bronchospasm.
Hematologic: agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.
Autoimmune: Systemic Lupus Erythematosus (SLE).
Skin and Mucous Membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctive reported for a beta blocker have not been associated with propranolol.
Genitourinary: male impotence, Peyronie's disease.