Picoprep Dosage/Direction for Use

Route of administration: Oral.
A low residue diet is recommended on the day prior to the procedure. A clear liquid diet is recommended on the day of the procedure. To avoid dehydration it is important to follow the liquid intake recommendation as advocated together with Sodium picosulfate + Magnesium oxide + Citric acid (PICOPREP) dosing while the effects of Sodium picosulfate + Magnesium oxide + Citric acid (PICOPREP) persist. Apart from the liquid intake together with the treatment regimen (PICOPREP + additional liquids), a normal, thirst driven intake of clear liquids is recommended. Clear liquids should include a variety of fruit juice without pulp, soft drinks, clear soup, tea, coffee (without milk, soy or cream). Do not drink only water.
Directions for reconstitution: Reconstitute the contents of one sachet in a cup of water (approximately 150 mL). Stir for 2-3 minutes, the solution should now become an off-white, cloudy liquid with a faint odour of orange. Drink the solution. If it becomes hot, wait until it cools sufficiently to drink.
Adults (including the elderly): (if the procedure is scheduled for the afternoon, it is recommended that the Split-Dose regimen should be used): Split-Dose Regimen (evening-before and day of the procedure): The first Sodium picosulfate + Magnesium oxide + Citric acid (PICOPREP) sachet is taken the night before the procedure, and the second is taken the next day, in the morning prior to the procedure.
On the day before the procedure: 1 sachet: The first reconstituted sachet is taken in the evening (e.g., 5:00 to 9:00PM), followed by at least five 250 mL drinks of clear liquids.
On the day of the procedure: 1 sachet: The second reconstituted sachet is taken in the morning (5-9 hours before the procedure), followed by at least three 250 mL drinks of clear liquids.
Clear liquids may be consumed until 1 hour before the time of the procedure.
Or DAY-BEFORE REGIMEN (evening-before the procedure only): The first Sodium picosulfate + Magnesium oxide + Citric acid (PICOPREP) sachet is taken in the afternoon or early evening and the second is taken approximately 6 hours later, the night before the procedure.
On the day before the procedure: 2 sachets: The first reconstituted sachet is taken in the afternoon or early evening (e.g., 4:00 to 6:00 PM), followed by at least five 250 mL drinks of clear liquids.
The second reconstituted sachet is taken in the late evening (e.g., 10:00 PM to 12:00 AM), followed by at least three 250 mL drinks of clear liquids.
Clear liquids may be consumed until 1 hour before the time of the procedure.
Children: The first dose reconstituted in water as directed, taken before 8 am on the day before the procedure. Second dose 6 to 8 hours later.
1-2 years: ¼ sachet morning, ¼ sachet afternoon.
2-4 years: ½ sachet morning, ½ sachet afternoon.
4-9 years: 1 sachet morning, ½ sachet afternoon.
9 and above: adult dose.