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Lactic acidosis is rare, but serious metabolic complication that can occur due to Metformin Hydrochloride accumulation. The reported incidence of lactic acidosis during Metformin Hydrochloride treatment is lower than 0.1 case per 1000 patient-years, and the mortality risk is even lower.
Lactic acidosis is a medical emergency that must be treated in a hospital setting. In a patient with lactic acidosis, the drug should be discontinued immediately and general supportive measures promptly instituted.
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