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Known hypersensitivity to diclofenac or other ingredients in the product.
Patients with complete or partial syndrome of nasal polyps, or in whom asthma, anaphylaxis, urticaria, rhinitis, or other allergic-type reactions are precipitated by aspirin or other NSAIDs. Severe, rarely fatal, anaphylactoid reactions to NSAIDs have been reported in such patients.
Patients with a history of GI bleeding or perforation related to previous NSAID therapy.
Patients with active gastric, duodenal or peptic ulcer, active GI bleeding or perforation, regional ulcer, gastritis or ulcerative colitis.
Patients with severe heart, liver or kidney failure.
Patients with established congestive heart failure (New York Heart Association II-IV), ischemic heart disease, or peripheral artery disease.
Cerebrovascular bleeding or other bleeding disorders.
Inflammatory bowel disease.
Known hyperkalemia.
Dengue fever, since NSAIDs may increase the risk of bleeding.
Third trimester of pregnancy, because of the risk of premature closure of the fetal ductus arteriosus and delay labor and birth.
Breastfeeding women, because of the potential for serious adverse reactions in breastfed infants.
Children and adolescents younger than 16 years old.
Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.
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