Mytensa Special Precautions

Losartan potassium/Amlodipine besilate (Mytensa) is contraindicated in pregnancy and should be used with care, at all, during breastfeeding. Losartan potassium/Amlodipine besilate (Mytensa) should be used with caution in patients with bilateral renal artery stenosis or stenosis of an artery to single kidney, aortic valve stenosis, and hypertrophic obstructive cardiomyopathy. Symptomatic hypotension may occur after initiation of Losartan potassium/Amlodipine besilate (Mytensa). Reduced doses must be considered in patients with hepatic impairment.
Use in Renal Failure: Severe renal impairment, may however, require a dosage reduction. Amlodipine is not dialyzable.
Use in lmpaired Hepatic Function: Losartan potassium/Amlodipine besilate (Mytensa) should be administered at lower doses in these patients.
Use in Heart Failure: Losartan potassium/Amlodipine besilate (Mytensa) may increase in patients with heart failure.
Porphyria: Safety has not been established.
Use in Children: Safety and efficacy has not been established.
Use in the Elderly: Elderly patients should start Losartan potassium/Amlodipine besilate (Mytensa) therapy at a lower dose.