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Patients with a history of hypersensitivity to the drug should not administer the drug.
Use in Children: Safety has not been established for low birth weight, neonatal, infant, and pediatric.
Use in the Elderly: There is no difference in incidence of adverse events in elderly compared with the non-elderly. However, be cautious because in general, elderly patients have physiological dysfunction it may affect the gastrointestinal symptoms.
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