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Pheochromocytomas due to the possibility of a hypertensive crisis, probably due to release of catecholamine from the tumor.
Patients in whom increased gastrointestinal motility might be dangerous, e.g. presence of gastrointestinal haemorrhage, mechanical obstruction or perforation.
Known hypersensitivity to metoclopramide. Note: patients sensitive to procaine and procainamide may be sensitive to metoclopramide.
Patients with porphyria.
Metoclopramide should not be used in patients with epilepsy since it may increase the frequency and severity of seizures.
Metoclopramide should not be administered to patients receiving other drugs which are likely to cause extrapyramidal reactions, since the frequency and severity of extrapyramidal reactions may be increased.
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