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Omeprazole overdosage has been reported rarely. Doses ranged from 320 to 900 mg (16 to 45 times of the usual recommended dose). Symptoms were transient and no serious clinical outcome has been reported.
Nausea, vomiting, dizziness, abdominal pain, diarrhea, headache, apathy, depression and confusion are reported from omeprazole overdosage.
No specific antidote for omeprazole overdosage is known.
Omeprazole are extensively protein bound and are not readily dialyzable. Treatment should be symptomatic and supportive.
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