Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved. If a longer course is necessary, it is recommended that treatment should be continued for more than four weeks without the patient's condition being observed. Repeated short courses of Clobetasol propionate may be used to control exacerbations. If continuous steroid treatment is necessary a less potent preparation should be used. In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effects of Clobetasol propionate can be enhanced, if necessary, by occluding the treatment area with polythene film. Only overnight occlusion is usually adequate to bring about a satisfactory response. Thereafter, improvement can usually be maintained by application without occlusion. Or as directed by the physician.