Locoa Dosage/Direction for Use

Posology: Esflurbiprofen (LOCOA) should be applied to the affected area once daily in adults. Maximum number of patches of Esflurbiprofen (LOCOA) to be used per day is two (2) patches.
Esflurbiprofen (LOCOA) is a topical patch with improved transdermal absorption and enhanced penetration into affected tissues; therefore, the maximum number which is two (2) patches per day will be sufficient. Moreover, the safety of 2 patches per day has been examined in clinical studies. The use of Esflurbiprofen (LOCOA) with any other anti-inflammatory agent with expected systemic effects should be avoided wherever possible. If such use is deemed necessary, it should be limited to a minimal level and the condition of the patient should be carefully monitored.
Elderly: Since elderly patients are more susceptible to adverse reactions, their condition should be carefully monitored during treatment.
Paediatric population: Safety has not been established in low-birth-weight babies, neonates, nursing infants, infants and children. [Clinical studies have only been performed in adults and there is no experience in the use for the previously mentioned patients.]
Method of administration: Esflurbiprofen (LOCOA) is applied to the affected area.
Esflurbiprofen (LOCOA) cannot be applied to the damaged skin or membrane and to the area of eczema or rash. Careful administration is required with attention to the skin condition of the application site.
Esflurbiprofen (LOCOA) should be detached slowly and carefully to prevent any damage to the skin.