Lizod Use In Pregnancy & Lactation

Fertility: In animals studies, linezolid caused a reduction in fertility.
Impairment of fertility: Linezolid reversibly decreased fertility and induced abnormal sperm morphology in adult male rats at exposure levels approximately equal to those expected in humans; possible effects of linezolid on the human male reproductive system are not known.
Tab: Pregnancy: There are limited data from the use of linezolid in pregnant women. Studies in animals have shown reproductive toxicity. A potential risk for humans exists.
Linezolid should not be used during pregnancy unless clearly necessary i.e. only if the potential benefit outweighs the theoretical risk.
Breast-feeding: Animal data suggest that linezolid and its metabolites may pass into breast milk and, accordingly, breast-feeding should be discontinued prior to and throughout administration.
IV: Pregnancy: There are no adequate data from the use of linezolid in pregnant women. Studies in animals have shown reproductive toxicity.
Linezolid should not be used during pregnancy unless clearly necessary i.e. only if the potential benefit outweighs the theoretical risk.
Lactation: Available pharmacodynamic/toxicological data in animals have shown excretion of linezolid/metabolites in milk.
Breast-feeding should be discontinued during treatment with linezolid.