Concomitant administration of calcium-containing drugs may cause or aggravate elevated serum calcium levels.
Drugs that form hard soluble compounds with calcium (e.g. tetracyclines, quinolones such as ciprofloxacin and norfloxacin as well as drugs containing iron, fluoride or estramustine) should not be taken at the same time with Ketoanalogues + Essential Amino Acids (Ketoxil) to avoid disturbed absorption of the active substance. An interval of at least two hours should elapse between the ingestion of Ketoanalogues + Essential Amino Acids (Ketoxil) and these drugs.
The susceptibility to cardioactive glycosides, and hence the risk for arrhythmia will increase since Ketoanalogues + Essential Amino Acids (Ketoxil) produces elevated serum calcium levels. Uremic symptoms improve under therapy with Ketoanalogues + Essential Amino Acids (Ketoxil). Thus, in case of aluminium hydroxide administration, the dose of this drug has to be reduced if necessary. Serum phosphate levels should be monitored for a decrease.
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