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As with other cephalosporin, anaphylactic shock cannot be ruled out even if a thorough patient history is taken. Anaphylactic shock requires immediate countermeasures such as intravenous epinephrine followed by a glucocorticoid. In rare case, shadows suggesting sludge have been detected by sonograms of the gallbladder. This condition was reversible on discontinuation of Ceftriaxone (KEPTRIX) therapy. In-vitro studies have shown that Ceftriaxone (KEPTRIX) can displace bilirubin from serum albumin. Caution should be exercised when considering Ceftriaxone (KEPTRIX) for neonates, especially prematures.
Use in Pregnancy: Although there is no experimental evidence of mutagenic or teratogenic effects.
Ceftriaxone (KEPTRIX) should not be used in pregnancy (particularly in the first trimester) unless absolutely indicated.
Use in Lactation: Ceftriaxone (KEPTRIX) is excreted in human milk, usually in low concentrations. Caution should be exercised if Ceftriaxone (KEPTRIX) is given to nursing mother.
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