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Patients with known hypersensitivity to propranolol.
Patients with history of bronchospasm, bronchial asthma, or chronic obstructive pulmonary disease.
Cardiac decompensation which is not adequately treated.
Sick sinus syndrome/SA-block.
Metabolic acidosis.
Second and third-degree heart block.
Patients prone to hypoglycemia, e.g. due to prolonged fasting or restricted counter regulatory reserve.
Cardiogenic shock.
Untreated phaeochromocytoma.
Severe bradycardia.
Severe hypotension.
Severe peripheral arterial disturbances.
Prinzmetal's angina.
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